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Apr 29, 2024 Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation

C. Cosson, R. Riou, D. Patoli, T. Niu, A. Rey, M. Groslambert, C. De Rosny, E. Chatre, O. Allatif, T. Henry, F. Venet, F. Milhavet, G. Boursier, A. Belot, Y. Jamilloux, E. Merlin, A. Duquesne, G. Grateau, L. Savey, A.T.J. Maria, A. Pagnier, S. Poutrel, O. Lambotte, C. Mallebranche, S. Ardois, O. Richer, I. Lemelle, F. Rieux-Laucat, B. Bader-Meunier, Z. Amoura, I. Melki, L. Cuisset, I. Touitou, M. Geyer, S. Georgin-Lavialle, and B.F. Py

Apr 15, 2024 Impaired Reprogramming of the Autophagy Flux in Maturing Dendritic Cells from Crohn’s Disease Patients with Core Autophagy Gene-Related Polymorphisms

Quiniou G, Andromaque L, Duclaux-Loras R, Dinet O, Cervantes O, Verdet M, Meunier C, Boschetti G, Viret C, Nancey S, Faure M and Rozières A, Autophagy. 2024 Apr 14, doi: 10.1080/15548627.2024.2338574.

Apr 04, 2024 A vaccine targeting antigen-presenting cells through CD40 induces protective immunity against Nipah disease

Mar 21, 2024 Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells effector functions

S.Wang, M.Prieux, S.de Bernard, M.Dubois, D.Laubreton , S.Djebali, M.Zala, C.Arpin, L.Genestier, Y.Leverrier, O.Gandrillon, F.Crauste, W.Jiang, J.Marvel

Mar 15, 2024 The macrophage–bacterium mismatch in persister formation

Trends in Microbiology; I. Dadole, D. Blaha, N. Personnic

Feb 21, 2024 Unmasking the potential of secretory IgA and its pivotal role in protection from respiratory viruses

Antiviral Res: Sinha D., Yaugel-Novoa M., Waeckel L., Paul S., Longet S. DOI: 10.1016/j.antiviral.2024.105823

Jan 04, 2024 Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients

R. Coudereau, G. Monneret, A-C. Lukaszewicz, B. F. Py, L. Argaud, M. Cour, F. Bidar, M. Gossez, F. Venet

Dec 20, 2023 NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway

Cui S, Xia T, Zhao J, Ren X, Wu T, Kameni M, Guo X, He L, Guo J, Duperray-Susini A, Levillayer F, Collard JM, Zhong J, Pan L, Tangy F, Vidalain PO, Zhou D, Jiu Y, Faure M, Wei Y. Nat Commun. 2023 Dec 19;14(1):8440. doi: 10.1038/s41467-023-44201-2. PMID: 38114531

Dec 04, 2023 Generation of a C57BL/6J mouse strain expressing the CD45.1 epitope to improve hematopoietic stem cell engraftment and adoptive cell transfer experiments

Laubreton D, Djebali S, Angleraux C, Chain B, Dubois M, Henry F, Leverrier Y, Teixeira M, Markossian S, Marvel J.

Dec 01, 2023 Pre–Covid-19, SARS-CoV-2–Negative Multisystem Inflammatory Syndrome in Children

The New England Journal of Medicine ; S. Benezech, L. Khoryati, A. Belot

Oct 27, 2023 Antigen specific activation of cytotoxic CD8+ T cells by Staphylococcus aureus infected dendritic cells

Friot A, Djebali S, Valsesia S, Parroche P, Dubois M, Baude J, Vandenesch F, Marvel J, Leverrier Y.

Sep 19, 2023 Pivotal role of tissue-resident memory lymphocytes in the control of mucosal infections: can mucosal vaccination induce protective tissue-resident memory T and B cells?

Front. Immunol.: Longet S. and Paul S. https://www.frontiersin.org/articles/10.3389/fimmu.2023.1216402/full

Jun 28, 2023 Proof-of-Concept Human Organ-on-Chip Study: First Step of Platform to Assess Neuro-Immunological Communication Involved in Inflammatory Bowel Diseases

Int. J. Mol. Sci.: Gabriel-Segard T., Rontard J., Miny L., Dubuisson L., Batut A., Debis D., Gleyzes M., François F., Larramendy F., Soriano A., Honegger T. and Paul S. https://www.mdpi.com/1422-0067/24/13/10568

Jun 13, 2023 Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations

Clinical Microbiology Reviews: Miguelena Chamorro B., De Luca K., Swaminathan G., Longet S., Mundt E., Paul S. https://journals.asm.org/doi/10.1128/cmr.00164-22

Jun 13, 2023 Mucosal Vaccination with Live Attenuated Bordetella bronchiseptica Protects against Challenge in Wistar Rats

Vaccines: Miguelena Chamorro B., De Luca K., Swaminathan G., Rochereau N., Majorel J., Poulet H. Chanut B., Piney L., Mundt E., Paul S. https://www.mdpi.com/2076-393X/11/5/982

May 24, 2023 Farnesoid X receptor alpha ligands inhibit HDV in vitro replication and virion infectivity.

Legrand AF, Lucifora J, Lacombe B, Ménard C, Michelet M, Foca A, Abrial P, Salvetti A, Rivoire M, Lotteau V, Durantel D, André P, Ramière C. Hepatol Commun. 2023 Apr 14;7(5):e0078.

Apr 14, 2023 Prior COVID-19 Immunization Does Not Cause IgA- or IgG-Dependent Enhancement of SARS-CoV-2 Infection

Vaccines: Yaugel-Novoa M., Noailly B., Jospin F., Berger A.E., Waeckel L., Botelho-Nevers E., Longet S., Bourlet T., Paul S. https://www.mdpi.com/2076-393X/11/4/773

Apr 14, 2023 Association of IFNAR1 and IFNAR2 with COVID-19 severity

The Lancet Microbe: Yaugel-Novoa M., Bourlet T., Longet S., Botehlo-Nevers E, Paul S. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00095-2/fulltext

Apr 06, 2023 mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice

Moreews M ; Mathieu AL, Pouxvielh K... Marçais A, Walzer T, Belot A

Mar 24, 2023 Covid-19: infection-vaccination combination best protects against reinfection with SARS-CoV-2

Several CIRI teams carried out this work, published in the journal Science Translational Medicine.

Mar 16, 2023 Prior SARS-CoV-2 infection enhances and reshapes spike protein-specific memory induced by vaccination

Mar 14, 2023 An inventory of adjuvants used for vaccination in horses: the past, the present and the future.

Carnet F, Perrin-Cocon L, Paillot R, Lotteau V, Pronost S, Vidalain PO.

Jan 12, 2023 Interferon-dependent and independent mechanisms drive Hepatitis Delta Virus interference on Hepatitis B Virus RNA production

Lucifora et al., Journal of Hepatology, 2023 / Team HepVir

Jan 12, 2023 Farnesoid X receptor alpha ligands inhibit hepatitis delta virus in vitro replication and virion infectivity

Legrand, Lucifora et al., Hepatology Communications, 2023 / Team VIRIMI and Team HepVir

Jan 01, 2023 Last publication form the team

Grass, V. et al., Communication Biology 2022, VIV Team.

Dec 13, 2022 Un monde de Virus, Médecine Science

Le numéro de décembre coordonné par Anna Salvetti (équipe HepVir) et Hélène Dutartre (équipe OR) et consacré à la présence et au rôle des virus dans la biosphère. https://medecinesciences.org/fr/ https://pic.twitter.com/hfctvoob1V

Dec 07, 2022 Induction of a strong and long-lasting neutralizing immune response by dPreS1-TLR2 agonist nanovaccine against HBV

Lamrayat et al., Antiviral Research, 2023 / Team HepVir

Dec 07, 2022 A stable hepatitis D virus-producing cell line for host target and drug discovery

Bach, Lucifora et al., Antiviral Research, 2023 / Team HepVir

Dec 07, 2022 Loss of hepatitis D virus infectivity upon farnesyl transferase inhibitor treatment associates with increasing RNA editing rates revealed by a new RT-ddPCR method

Verrier et al., Antiviral Research, 2022 / Team HepVir

Nov 30, 2022 What role for cellular metabolism in the control of hepatitis viruses?

Olivier Diaz, Pierre-Olivier Vidalain1, Christophe Ramière, Vincent Lotteau and Laure Perrin-Cocon. Front. Immunol. 13:1033314.

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