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Kick-off of the industrial chair VIRESP
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On Wednesday January 24, 2024, Université Claude Bernard Lyon 1 (UCBL), Hospices Civils de Lyon (HCL)
(HCL), the French National Research Agency (ANR) and Sanofi officially launched the
the VIRESP industrial chair, a research project focusing on the development of
techniques and tools for analyzing the risk of infection and the morbidity rate of diseases
in different populations, but also to determine the benefits of vaccination programs.
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Antibiotic resistance: How some bacteria acquire resistance genes from their environment?
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Antibiotic resistance has made certain infections, sometimes common, such as urinary and respiratory infections, impossible to treat, representing a major setback in the medical care of human and animal patients. This resistance has thus become a major health issue, which has led the WHO (World Health Organization) to establish a list of bacteria in which antibiotic resistance is particularly worrying.In a new study published in the journal mBio, we focused on one of these bacteria that are particularly resistant to antibiotics, Acinetobacter baumannii. The latter is responsible for many opportunistic and nosocomial infections. We have determined the mechanisms that allow this bacterium to rapidly acquire resistance genes from neighboring bacteria.
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Charpentier X - Horigene
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COVID-19: Multisystem Inflammatory Syndrome in Children existed before the pandemic
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During the COVID-19 pandemic, multisystemic inflammatory syndrome affected 1,100 children. Since this first description in 2020, CIRI researchers, HCL clinicians and other international collaborators have discovered that this syndrome existed before COVID-19, and that other infectious agents could lead to this severe inflammatory syndrome in children. These findings are published in the New England Journal of Medicine.
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Walzer T - LYACTS
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Actualités
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Autophagy, a key role in the pathophysiology of Crohn's disease
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In a new study published in the journal Autophagy, CIRI researchers have shown for the first time that, in patients with Crohn's disease, the expression of autophagic gene variants strongly affects autophagic dynamics, known as autophagic flux.
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Impact of vaccination on induction of mucosal immunity with mRNA vaccines against Covid-19 epidemic.
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Teams from the Immunology Department of the Pitié-Salpêtrière AP-HP hospital, Inserm and Sorbonne University, coordinated by Prof. Guy Gorochov, have conducted a study on the ability of Covid-19 mRNA vaccines to induce a mucosal immune response. CIRI members took part in this study. The results were published in JAMA Network Open on April 23, 2024.
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Launch of the Chaire industrielle REVIDA
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On october 11, the Chaire industrielle REVIDA about respiratory infectious diseases, led by the researcher Sophie Trouillet-Assant (UCBL/HCL), was officially launched by the Université Claude Bernard Lyon 1, the Hospices Civils de Lyon, and bioMérieux, with the support of the Agence nationale de la recherche. It should enable the improvement of the capacity of health systems to face the emerging of new respiratory diseases.
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HERVCOV: A european project coordinated by Branka Horvat
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The protein that opens doors to the medicine of the future and treatment of COVID-19
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Horvat B - IbIV
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Recent books published by members of the CIRI
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Members of the CIRI contributed to two books that were recently published. One is about the history of microbiology, and the other tackles research progress linked to the COVID-19 pandemic.
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CERP/PHE3ID team awarded the Shapemed@Lyon call "Projets d'amorçage"
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The PHE3ID/CERP research team has been awarded with one of the first Projets d’Amorçage supported by SHAPE-Med@Lyon
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Rare Disease Day 2024
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February 29, 2024 is Rare Disease Day. This is an opportunity to thank the clinicians and researchers who are advancing research on this subject at CIRI, as well as our patients!
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