Grants and Funding
ANR generic call AAPG2022-MucRNAvax
Design and evaluate LipoParticulate mRNA vaccine carrier, able to cross physical barriers of the respiratory tract and to induce mucosal immune response against viral respiratory infectious diseases
2022-2026
Coordinator : LBTI
Parners : VirPath, GIMAP, IVPC
NSB CNRS (soutien COVID19)
Drug repurposing approaches for COVID-19.
Coordinateur VirPath
PSPC-COVID-19 (PIA) BPI
Solutions thérapeutiques, préventives ou curatives contre le COVID-19.
Coordinateur : OSIVAX, Project leaders : INSERM, Cochin Vaccine Evaluation Center APHP, Cynbiose and Virapth
Projet ANR RA-COVID19 - CHROMACoV
Role of pro-inflammatory cytokines, PML nuclear bodies, and the HIRA histone chaperone complex in epigenetic changes associated to SARS-CoV-2 infection.
Coordinateur: INMG; Partenaires : VirPath, CRSA/Sorbonne Université.
Fondation ARC EPONAC
Proteomics, cellular co-receptor and SARS-CoV-2.
Coordinateur : CRCL; VirPath (Partners)
Installations de Recherche et d’Innovation Centrées Entreprises, IRICE, Région Auvergne Rhône-Alpes, Union Européenne FEDER
Innobiovir « Innovation Bioproduction Virus » : Alliance de plateformes technologiques dans le domaine des vaccins viraux et leurs procédés de production.
2020 – 2025. Teams : VirNext, VirPath (co-coordinateur), Lagepp UMR-CNRS 5007, IUT Génie biologique UCBL1.
IMI2-RIA H2020-JTI-IMI2-2020-21-single-stage
Projet CARE (Corona Accelerated R&D in Europe) 35 M€.
Coordinateur : INSERM, Project leaders : Janssen Pharmaceutica et Takeda, Partners : CEA, Helmholtz-Zentrum, LUMC, Boehringer Ingelheim, Novartis, Pfizer, Merck, Bayer…).
REACTing – Projet initiative Anti2019-nCoV
Repositionnement thérapeutique.
VirPath (coordinateur)
REACTing – Projet initiative
In vivo titration of the SARS-CoV-2 in Cynomolgus Macaques.
IDMIT CEA (coordinateur); Partenaires : VirPath, Institut Pasteur Paris
Merieux research grant
Repositionnement thérapeutique de médicaments.
VirPath (Coordinateur)
Instituts de recherche en santé du Canada
Innovative therapeutic approaches for the 2019-novel coronavirus (SARS-CoV-2).
CHUQ, Université Laval, Québec (coordinateur); Partners: International Vaccine Centre (VIDO-InterVac) University of Saskatchewan, National Research Council NRC Ottawa, VirPath
Région AURA - COVIBIOSE
Mise au point d’un modèle primate non humain d’infection par le virus SARS-CoV-2 pour l’évaluation de candidats thérapeutique.
VirPath (co-coordinateur), Cynbiose SA (co-coordinateur), Vetagrosup
ANR Flash-COVID-19 – Anti-CoV-Path
Pathogenesis of SARS-CoV-2 infection in NHP model : insights for treatment and prévention.
IDMIT CEA (coordinator); Partners: Institut Pasteur, INSERM UMR 1137, CIIL U1019, UMR9017, IBS-CHUGA, VirPath
ANR Flash-COVID-19 – AM-CoV-Path
Approche thérapeutique.
CIIL U1019, UMR9017 (coordinator); Partners: IDMIT CEA, VirPath
ANR Flash-COVID-19 – COVID-I2A Therapy
Antiviral approach against the coronavirus SARS-CoV-2.
CNRS FR3636 Paris Descartes Mort cellulaire programmée et signalisation (coordinator); Partners: INSERM UMR_S94I Paris Diderot Génétique des Virus et Pathogénèse des Maladies Virales, Institut de Génétique UMR 9002, Montpellier, VirPath
AAP Flash COVID Sorbonne University – Projet CoVNucleovir.
INSERM U938 CRSA, SU (coordinateur); Partenaires : CNRS UMR 8226 SU, INSERM U938 CRSA, SU, VirPath
AAP Région Hauts de France – Projet CritiSARS2.
CHU Lille (coordinateur); Partenaires: CRB et CIC, CHU Lille, MCV, CIIL, INSERM U1019-CNRS UMR9017, ULR3610 “Viral pathogenesis”, VirPath
Maturation COVID-19 – SATT PULSALYS
Antiviral approach against SARS-CoV-2.
VirPath (coordinator)
Projet de maturation Glycoflu – SATT Linksium, Grenoble
Développement et évaluation de nouveaux composés sialosides issus d’un procédé microbiologique industriel de production, ayant un potentiel d’inhibiteur de virus influenza.
2020 – 2021. Teams : CERMAV CNRS UPR5301/coordinateur, VirNext, VirPath.
R&D BOOSTER Région Auvergne Rhône-Alpes, BPI France, EU FEDER
Development and characterization of a new pre-clinical NHP model of HMPV infection to evaluate repurposed drugs.
2020-2021 - Teams: Signia Therapeutics (coordinator), VirPath and Cynbiose
ANR AAP19 METAVAC-T17
Characterization and up scaling of a DuckCeltTM-T17 cell suspension culture process for the production of a new live-attenuated hRSV/hMPV chimeric METApneumovirus-based VACcine.
2019-2022 - Teams : VirPath (coordinator), LAGEPP UMR-CNRS 5007 and UVIM-UR0892
IDEXLYON Breakthrough program WANTED.
(Which Atmospheric Nanoparticles Trigger hEatlh Diseases?).
2018-2021 - Teams : IRCELYON (Principal Investigator), CarMeN, ISA, Legionella pathogenesis team and VirPath
METAVAC - Maturation Program funded by the Technology Transfer Accelerator Office PULSALYS. Development of a new live attenuated viral vaccine and optimized upscalable avian cell line-based process for production.
2019-2020 VirPath (Principal investigator)
REPURPOSING - Maturation Program funded by the Technology Transfer Accelerator Office PULSALYS.
Pre-clinical evaluation of a repurposed drug for new antimicrobial indication.
2019-2020 VirPath (Principal investigator)
VLM grant (Vaincre la Mucoviscidose)
Study of co-infections between influenza & bacteria in healthy versus Cystic Fibrosis 3D reconstituted human airway epithelia.
2018 - VirPath (Principal Investigator)
Fondation Air Liquide: COEPIMUS
Mieux comprendre les mécanismes de pathogenèse entre virus et bactéries à l’échelle de l’épithélium respiratoire dans le contexte des pathologies respiratoires chroniques.
2019-2020 VirPath (Principal investigator)
CIRI Funding 2018
The lung-on-a-chip as a new platform for studying respiratory diseases.
2018 - Teams : Legionella pathogenesis (Principal investigator), Staphylococcus pathogenesis and VirPath
FINOVI 11th : COEPI
Signatures of bacterial-viral co-infections in healthy versus Cystic Fibrosis 3D reconstituted human airway epithelia.
2017 - VirPath (Principal Investigator)
CSIC Uruguay R&D Program.
Design of TWIN compounds with antiviral activity against influenza and respiratory syncytial viruses.
2017 – University of the Republic Uruguay ; VirPath (Co-Principal Investigator)
FINOVI 10th: IDEA-FLU
Innovative nano DElivery systems for Influenza Antigens.
2016 - CEA Leti ; Institut Albert Bonniot (IAB) U823 INSERM Université Grenoble
CIRI Funding 2017
Study of the effect of fusion inhibitory peptides in the prevention and treatment of influenza virus infection.
2017 - Teams : Immunobiology of Viral infections and VirPath
PHRC : FLUNEXT Clinical trial.
Confirmation of the Antiviral Effects of repurposed drugs.
Jan. 2016 - CHRU de Lille ; VirPath.
Triggersep label.
ANR : Psi-FLU project
Sequence and structure of the packaging signals of the influenza A virus genome.
Sept. 2015 - IBMC Architecture et Réactivité de L'ARN CNRS UPR 9002
FINOVI 9th: FLUCUBE
Purification of in vivo influenza virus crystalline structures in order to characterize the complete NS1 protein structure
2015 - IBS ; VirPath (Principal investigator)
CMIRA Accueil PRO (Auvergne-Rhône-Alpes)
Programme d’aide à la mobilité des chercheurs étrangers de la région Auvergne-Rhône-Alpes.
2015 VirPath (Principal Investigator)
ANR : OPTIVAC project
leveraging On cellular immune resPonse To Improve flu VACcines.
Jan. 2014 - Imaxio ; CIRI U1111 INSERM - UMR 5308 CNRS - ENS Lyon - UCBL1
ANR : BioVirSafe (LabCom) project
Laboratoire Commun de recherche et développement de biocides pour la maîtrise des contaminations microbiologique.
Jan. 2014 - PSA (Produits Sanitaires Aéronefs, Paris) ; VirPath (Principal investigator)
ANR-PRTS : Cov-Sign project
Identification of novel inhibitors against emerging human coronaviruses MERS-CoV and SARS-CoV from in vivo transcriptionnel.
Jan. 2014 - Institut Pasteur - CNRS UMR3569 ; CIIL Inserm U1019 CNRS UMR8204 ; CHRU de Lille ; ProfileXpert ; VirPath (Principal investigator)
Lyon Biopole label.
FP7 Marie Curie actions: FLU-MAL VLP project
Chimeric Influenza-VLP used as vaccine platform for presentation of foreign antigens, application to Malaria antigens.
Jan. 2013 - VirPath (Principal investigator)
CMIRA program (Rhône-Alpes)
Programme de coopération structurante de la région Rhône-Alpes avec la région de Québec.
Jan. 2013 VirPath (Principal investigator)
PHRC : FLUMED Clinical trial (NCT01546506).
Confirmation of the Antiviral Effects of Midodrine Identified With a Gene Expression Signature-based Screening of Inluenza A Virus Infected Cells.
Jan. 2012 - Hospices Civils de Lyon ; Université Claude Bernard Lyon 1 ; Virpath (Principal investigator)
FUI : COV-KO project
Réalisation d’appareils sécurisés (autonomes et intégrés) de traitement de l’air intérieur « 0 » COV, « 0 » odeur.
Jan. 2012 – BMES ; Brochier ; Tera Environnement ; ALDEBO ; ETHERA ; Atlantic ; IRCE Lyon UMR 5256 CNRS
Axelera Label
BQIP : VirNext platform
Bonus qualité relations industrielles plateformes 2012.
Jan. 2012 – VirNext ; Université Claude Bernard Lyon 1; Ezus
Maturation de Projets Innovants : FLUVAC project
New compounds
Jan. 2012 – Université Claude Bernard Lyon 1 ; SATT Pulsalys ; VirPath (Principal Investigator)
FUI : FLURIAD project
Mucous administration of anti-influenza vaccine.
Jan. 2011 - Onxeo ; Université Paris Sud EA 401; Sogeval ; Gredeco ; CHU de Nice.
Medicen label.
APP Recherche Clinique Translationnelle : FLUNEXT project
Transcriptomic signature of influenza from pandemic H1N1 infected patients.
Jan. 2010 - Inserm ; DHOS
BQIP : FLUVAX project
Bonus Qualité Relations Industrielles (UCBL).
Jan. 2010 – Université Claude Bernard Lyon 1 ; SATT Pulsalys ; VirPath (Principal Investigator)
Maturation de Projets Innovants : FLUGP project
Optimisation du procédé de production des glycoprotéines des semences vaccinales.
Jan. 2010 - UCBL ; Lyon Science Transfert
FUI : SAVAB project.
Anti-microbiologic systems.
Jan. 2010 - Aelovre.
Pegase label.