News
Dengue Virus dependence on glucokinase activity and glycolysis Confers Sensitivity to NAD(H) biosynthesis inhibitors
Ogire E, Perrin-Cocon L, Figl M, Kundlacz C, Jacquemin C, Hubert S, Aublin-Gex A, Toesca J, Ramière C, Vidalain PO, Mathieu C, Lotteau V, Diaz O. Antiviral Res. 2024 Jun 22;228:105939. doi: 10.1016/j.antiviral.2024.105939.
[Role of cellular metabolism in the control of chronic viral hepatitis].
Olivier Diaz, Anne-Flore Legrand*, Walid El-Orch*, Florentine Jacolin*, Vincent Lotteau, Christophe Ramière, Pierre-Olivier Vidalain & Laure Perrin-Cocon. Med Sci (Paris). 2023 Oct;39(10):754-762. doi: 10.1051/medsci/2023125. French.
Farnesoid X receptor alpha ligands inhibit HDV in vitro replication and virion infectivity.
Legrand AF, Lucifora J, Lacombe B, Ménard C, Michelet M, Foca A, Abrial P, Salvetti A, Rivoire M, Lotteau V, Durantel D, André P, Ramière C. Hepatol Commun. 2023 Apr 14;7(5):e0078.
An inventory of adjuvants used for vaccination in horses: the past, the present and the future.
Carnet F, Perrin-Cocon L, Paillot R, Lotteau V, Pronost S, Vidalain PO.
What role for cellular metabolism in the control of hepatitis viruses?
Olivier Diaz, Pierre-Olivier Vidalain1, Christophe Ramière, Vincent Lotteau and Laure Perrin-Cocon. Front. Immunol. 13:1033314.
A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity
During liver carcinogenesis, the first enzyme of glycolysis GCK is replaced in hepatocytes by the hexokinase HK2. We show that it critically contributes to metabolic reprogramming and inhibition of innate immunity associated to liver cancer development.
Recherche COVID dans l'équipe VIRIMI
meta-analysis of virus-host protein-protein interactions for 13 coronaviruses including #SARS-CoV2, #MERSCoV and #SARSCoV