News
Farnesoid X receptor alpha ligands inhibit HDV in vitro replication and virion infectivity.
Legrand AF, Lucifora J, Lacombe B, Ménard C, Michelet M, Foca A, Abrial P, Salvetti A, Rivoire M, Lotteau V, Durantel D, André P, Ramière C. Hepatol Commun. 2023 Apr 14;7(5):e0078.
An inventory of adjuvants used for vaccination in horses: the past, the present and the future.
Carnet F, Perrin-Cocon L, Paillot R, Lotteau V, Pronost S, Vidalain PO.
What role for cellular metabolism in the control of hepatitis viruses?
Olivier Diaz, Pierre-Olivier Vidalain1, Christophe Ramière, Vincent Lotteau and Laure Perrin-Cocon. Front. Immunol. 13:1033314.
A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity
During liver carcinogenesis, the first enzyme of glycolysis GCK is replaced in hepatocytes by the hexokinase HK2. We show that it critically contributes to metabolic reprogramming and inhibition of innate immunity associated to liver cancer development.
Recherche COVID dans l'équipe VIRIMI
meta-analysis of virus-host protein-protein interactions for 13 coronaviruses including #SARS-CoV2, #MERSCoV and #SARSCoV