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Understanding infectious diseases to better control them

The Centre International de Recherche en Infectiologie (CIRI) is a joint research unit of the Lyon 1 University, Inserm, CNRS and the ENS de Lyon in partnership with VetAgro Sup, the Institut Pasteur and the Hospices Civils de Lyon. The CIRI gathers the scientific and medical research communities with complementary disciplinary backgrounds grouped in 3 specialties working together with the objective to understand host-microbe interactions to better fight infectious diseases.

Discover the CIRI: General presentation, Teams, Teaching, Clinical research, Organization, The 3 specialties and Transversal projects, Jobs and internship offers, Contact & Localization.





Apr 13, 2022 Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome-enriched vesicles.

Michel Record, Mehdi Attia, Kevin Carayon, Laly Pucheu, Julio Bunay, Régis Soulès, Silia Ayadi, Bruno Payré, Laure Perrin-Cocon, Florence (...)

Mar 10, 2022 A new mechanism for perversion of the viro-induced nuclear pore

Bertrand Boson, Chloé Mialon, Konstanze Schichl, Solène Denolly, François-Loïc Cosset. mBio

Feb 04, 2022 Predictive factors of a viral neutralizing humoral response after a third dose of COVID-19 mRNA vaccine in kidney transplant recipients

by X.Charmetant, M.Espi (...) and O.Thaunat, American Journal of Tranplantation 2022, DOI : 10.1111/ajt.16990


Sep 10, 2021 Selective Autophagy Receptors in Antiviral Defense.

Viret C, Duclaux-Loras R, Nancey S, Rozières A, Faure M.Trends Microbiol. 2021 Sep;29(9):798-810.

Apr 19, 2021 Regulatory Networks of the T4SS Control: From Host Cell Sensing to the Biogenesis and the Activity during the Infection

Jaboulay et al. J Mol Biol 2021 April 30

Mar 30, 2021 Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond

Pastor F et al., Frontiers in Microbology, 2021 / Team HepVir



Jul 04, 2022 Séminaire CIRI : Pr. Stephan URBAN

"Discovery and development of Hepcludex/bulevirtide, the first approved drug for chronic Hepatitis (...)

Jul 12, 2022 CIRI seminar: Pr. Paul GUICHARD

"Expansion microscopy for Structural cell biology: from centriole architecture to human diseases"

Last conferences

Jun 15, 2022 IRCI 2022

Immune Response in Cancer and Infection

Jun 07, 2022 Réunion annuelle AC42

Réseau National Hépatites de l'ANRS | Maladies Infectieuses Emergentes

May 31, 2022 SFM Mycodays Lyon 20 – 22 juin
Mar 15, 2022 Journées scientifiques de l'ANRS

Maladies infectieuses émergentes

Jan 26, 2022 CFATG10

10èmes Journées Scientifiques de l’Autophagie

Last events

Jan 26, 2022 Kick-off meeting Equipex InfectioTron
May 10, 2021 Interview de Olivier Hequet

Etude COVIDEP : un essai clinique pour limiter la phase "d'hyper inflammation" liée au Covid-19

Thesis defenses

Oct 05, 2021 PhD defense of Marion Delphin, team HepVir

Polarization of Hepatic Macrophages by HBsAg, a means to an end for viral maintenance