Comprendre les maladies infectieuses pour mieux les contrôler
Le Centre International de Recherche en Infectiologie (CIRI) est une unité mixte de l’Université Lyon 1, de l’Inserm, du CNRS et de l’ENS de Lyon, en partenariat avec VetAgro Sup, l'Institut Pasteur et les Hospices Civils de Lyon. Le CIRI rassemble des communautés de recherche scientifique et médicale d’horizons disciplinaires complémentaires regroupés en 3 spécialités qui travaillent ensemble avec pour objectif principal la compréhension des interactions entre les microbes et leurs hôtes afin de mieux lutter contre les maladies infectieuses.
- Three specialities working together
Mieux nous connaître
- Publications
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The New England Journal of Medicine ; S. Benezech, L. Khoryati, A. Belot
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Front. Immunol.: Longet S. and Paul S. https://www.frontiersin.org/articles/10.3389/fimmu.2023.1216402/full
- Vindry C, Guillin O, Wolff P, Marie P, Mortreux F, Mangeot PE, Ohlmann T, Chavatte L. Nucleic Acids Res. 2023 May 31:gkad482. doi: 10.1093/nar/gkad482.
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Int. J. Mol. Sci.: Gabriel-Segard T., Rontard J., Miny L., Dubuisson L., Batut A., Debis D., Gleyzes M., François F., Larramendy F., Soriano A., Honegger T. and Paul S. https://www.mdpi.com/1422-0067/24/13/10568
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Clinical Microbiology Reviews: Miguelena Chamorro B., De Luca K., Swaminathan G., Longet S., Mundt E., Paul S. https://journals.asm.org/doi/10.1128/cmr.00164-22
- Vaccines: Miguelena Chamorro B., De Luca K., Swaminathan G., Rochereau N., Majorel J., Poulet H. Chanut B., Piney L., Mundt E., Paul S. https://www.mdpi.com/2076-393X/11/5/982
- Actualités
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Durant la pandémie COVID-19, le syndrome inflammatoire multi-systémique a touché 1100 enfants. Depuis cette première description en 2020, des chercheurs du CIRI, des cliniciens des HCL et d’autres collaborateurs internationaux, ont découvert que ce syndrome existait avant le COVID-19 et que d’autres agents infectieux pourraient conduire à ce syndrome inflammatoire grave de l’enfant. Ces résultats sont publiés dans la revue New England Journal of Medicine.
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Among the 11 laureates of the PEPR MIE 2023 call for projects (ANRS|Emerging Infectious Diseases), 6 projects involve CIRI teams. Their common aim is to better understand, prevent and control the emergence or re-emergence of infectious diseases.
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The PHE3ID/CERP research team has been awarded with one of the first Projets d’Amorçage supported by SHAPE-Med@Lyon
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On october 11, the Chaire industrielle REVIDA about respiratory infectious diseases, led by the researcher Sophie Trouillet-Assant (UCBL/HCL), was officially launched by the Université Claude Bernard Lyon 1, the Hospices Civils de Lyon, and bioMérieux, with the support of the Agence nationale de la recherche. It should enable the improvement of the capacity of health systems to face the emerging of new respiratory diseases.
- Nous rejoindre
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We are looking to hire one Postdoctoral Researcher to work on the project EASIER-COHORT: ExtrAction of Symptoms from electronIc hEalth Records to create automatic COHORTs funded by the SHAPE-Med@Lyon initiative. The candidate will have a contract with Lyon 1 University, and he/she will spend his/her time between the LIRIS and the CERP research laboratories.
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The planned appointment date will be halfway of 2022-2026, in order to prepare the candidate to take over the management of the Institute starting on 1st January 2027 for a first five-year term. The date of integration into the Institute, ideally mid-2024, should allow a strong involvement in the establishment of the preparation of the CIRI next term project and a transition period with the present Director, François-Loïc Cosset.
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A 2-year post-doctoral position for a highly motivated and talented postdoctoral fellow is available in the team of Dr Marc Vocanson at the Centre International de Recherche en Infectiologie (CIRI), in Lyon, France.
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Le candidat retenu travaillera dans le cadre d'un projet collaboratif JPIAMR DRUID (NOBACT) financé par l'ANR et portant sur l’évaluation de l’activité d’un nouvel antibiotique inhibiteur de CopA, une ATPase de type P transportant le cuivre, et identifier son impact sur la physiologie bactérienne.
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The I2BA team is recruiting a post-doctoral fellow to work on Francisella T6SS and its effectors (more details below).
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The IbIV team recruits a Data Manager, who will be responsible for gathering, organizing and validating all the data collected as part of a European project, focusing on COVID-19 and Long COVID.
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EVIR Team: "Genetic reprogramming of B cells to enhance their therapeutic properties before autologous transfer"
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Doctoral thesis under the joint co-supervision of Sonia Longhi (head of the “Structural Disorder and Molecular Recognition” team, AFMB lab, Marseille, France) and Cyrille Mathieu (head of the NITROVIRE team, CIRI, Lyon, France. Project: “Interfering with viral factories as an antiviral strategy against Nipah virus and Paramyxovirinae” (NIPAH-LISA)
- Agenda
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The annual congress of the French Virologie Society (SFV) will take place in Brussels (Belgium) in 2024!
- « Deltavirus infection in human and animal cells »
- « From Virus-Host Cell Interaction to Developing a Vaccine Against Crimean-Congo Hemorrhagic Fever Virus »
- « Developing small molecule inhibitors of Lipoteichoic acid synthesis » & « Group A streptococcus and inflammasomes: role of C4BP » Séminaire annulé
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Cette journée, ouverte à tous (médecins, étudiants et chercheurs), sera l'occasion de partager les travaux scientifiques en immunologie clinique et translationnelle des praticiens et chercheurs des Hospices Civils de Lyon.
- "tbc"
