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Actualités

Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus

Nilanshu Manocha, Daphné Laubreton, Xavier Robert, Jacqueline Marvel, Virginie Gueguen-Chaignon, Patrice Gouet, Prashant Kumar and Madhu Khanna

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Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells effector functions

S.Wang, M.Prieux, S.de Bernard, M.Dubois, D.Laubreton , S.Djebali, M.Zala, C.Arpin, L.Genestier, Y.Leverrier, O.Gandrillon, F.Crauste, W.Jiang, J.Marvel

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Antigen specific activation of cytotoxic CD8+ T cells by Staphylococcus aureus infected dendritic cells

Friot A, Djebali S, Valsesia S, Parroche P, Dubois M, Baude J, Vandenesch F, Marvel J, Leverrier Y.

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Generation of a C57BL/6J mouse strain expressing the CD45.1 epitope to improve hematopoietic stem cell engraftment and adoptive cell transfer experiments

Laubreton D, Djebali S, Angleraux C, Chain B, Dubois M, Henry F, Leverrier Y, Teixeira M, Markossian S, Marvel J.

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The mystery of the disappearing lymphocytes

Lymphocytes are immune cells that play vital roles in fighting infections. The most well-known lymphocytes are the T cells and B cells of the adaptive immune system. In the 1950s and 1960s, scientists performed experiments to follow lymphocytes on their journey around the body, which helped us to work out where they go and what they do. This work laid the foundation for everything we know about T cells today, including how they become activated to fight infections and how they form memory populations that provide long-lasting immunity.

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CD8 memory precursor cell generation is a continuous process

Helena Todorov, Margaux Prieux, Daphne Laubreton, Matteo Bouvier, Shaoying Wang, Simon de Bernard, Christophe Arpin, Robrecht Cannoodt, Wouter Saelens, Arnaud Bonnaffoux, Olivier Gandrillon, Fabien Crauste, Yvan Saeys, Jacqueline Marvel

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