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You are here: Home / Teams / Marvel J - ICL / Publications

Publications

Publications

 

2021

Polyclonal expansion of TCR Vbeta 21.3+ CD4+ and CD8+ T cells is a hallmark of Multisystem Inflammatory Syndrome in Children.  Moreews M, Le Gouge K, Khaldi-Plassart S, Pescarmona R, Mathieu AL, Malcus C, Djebali S, Bellomo A, Dauwalder O, Perret M, Villard M, Chopin E, Rouvet I, Vandenesh F, Dupieux C, Pouyau R, Teyssedre S, Guerder M, Louazon T, Moulin-Zinsch A, Duperril M, Patural H, Giovannini-Chami L, Portefaix A, Kassai B, Venet F, Monneret G, Lombard C, Flodrops H, De Guillebon JM, Bajolle F, Launay V, Bastard P, Zhang SY, Dubois V, Thaunat O, Richard JC, Mezidi M, Allatif O, Saker K, Dreux M, Abel L, Casanova JL, Marvel J, Trouillet-Assant S, Klatzmann D, Walzer T, Mariotti-Ferrandiz E, Javouhey E, Belot A. Sci Immunol. 2021 May 25;6(59):eabh1516. doi: 10.1126/sciimmunol.abh1516. PMID: 34035116

PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging
Huna A, Griveau A, Vindrieux D, Jaber S, Flaman JM, Goehrig D, Azzi L, Médard JJ, Djebali S, Hernandez-Vargas H, Dante R, Payen L, Marvel J, Bertolino P, Aubert S, Dubus P, Bernard D.Cell Death Dis. 2021 Feb 16;12(2):190. doi: 10.1038/s41419-021-03468-3. PMID: 33594040

Modeling and characterization of inter-individual variability in CD8 T cell responses in mice.
Audebert C, Laubreton D, Arpin C, Gandrillon O, Marvel J, Crauste F. In Silico Biol. 2021 Feb 3. doi: 10.3233/ISB-200205. PMID: 3355489

Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging.
Ziegler DV, Vindrieux D, Goehrig D, Jaber S, Collin G, Griveau A, Wiel C, Bendridi N, Djebali S, Farfariello V, Prevarskaya N, Payen L, Marvel J, Aubert S, Flaman JM, Rieusset J, Martin N, Bernard D. Nat Commun. 2021 Feb 1;12(1):720. doi: 10.1038/s41467-021-20993-z. PMID: 33526781

2020

The Inflammasome Adaptor ASC Delays UV-Induced Skin Tumorigenesis in Beta HPV38 E6 and E7 Transgenic Mice.
Magnotti F, Valsesia S, Gupta P, Flechtenmacher C, Contard P, Viarisio D, Venuti A, Wencker M, Tommasino M, Marvel J, Henry T. J Invest Dermatol. 2021 Jan;141(1):236-238.e2. doi: 10.1016/j.jid.2020.04.028. Epub 2020 May 26. PMID: 32470340

Zeb1 represses TCR signaling, promotes the proliferation of T cell progenitors and is essential for NK1.1+ T cell development.

Zhang J, Wencker M, Marliac Q, Berton A, Hasan U, Schneider R, Laubreton D, Cherrier DE, Mathieu AL, Rey A, Jiang W, Caramel J, Genestier L, Marçais A, Marvel J, Ghavi-Helm Y, Walzer T. Cell Mol Immunol. 2020 May 12. doi: 10.1038/s41423-020-0459-y. Online ahead of print. PMID: 32398809
 

2019

OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes.
Del Campo J, Pizzorno A, Djebali S, Bouley J, Haller M, Pérez-Vargas J, Lina B, Boivin G, Hamelin ME, Nicolas F, Le Vert A, Leverrier Y, Rosa-Calatrava M, Marvel J, Hill F. NPJ Vaccines. 2019 Jan 23;4:4. doi: 10.1038/s41541-019-0098-4. eCollection 2019. PMID: 30701093

Model-Based Assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-Cell Immune Responses.
Girel S, Arpin C, Marvel J, Gandrillon O, Crauste F. Front Immunol. 2019 Feb 19;10:230. doi: 10.3389/fimmu.2019.00230. eCollection 2019. PMID: 30842771

2018

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.
Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, Grau M, Macari C, Bauché D, Dumitrescu O, Rasigade JP, Lippens S, Plateroti M, Kress E, Cesaro A, Bondu C, Rothermel U, Heikenwälder M, Lina G, Bentaher-Belaaouaj A, Marie JC, Caux C, Trinchieri G, Marvel J, Michallet MC.
Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10404-10409. doi: 10.1073/pnas.1722372115

Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
Griveau A, Wiel C, Le Calvé B, Ziegler DV, Djebali S, Warnier M, Martin N, Marvel J, Vindrieux D, Bergo MO, Bernard D.
Aging Cell. 2018 Sep 14:e12835. doi: 10.1111/acel.12835

Antigen-induced but not innate memory CD8 T cells express NKG2D and are recruited to the lung parenchyma upon viral infection.
M. Grau, S.Valsesia, J. Mafille, S.Djebali, M.Tomkowiak, AL Mathieu, D. Laubreton, S. de Bernard, PE Jouve, E. Ventre, L. Buffat, T. Walzer, Y. Leverrier, J. Marvel.
J Immunol. 2018 Apr 9. pii: ji1701698. doi: 10.4049/jimmunol.1701698

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing.
Teixeira M, Py BF, Bosc C, Laubreton D, Moutin MJ, Marvel J, Flamant F, Markossian S.
Sci Rep. 2018 Mar 13;8(1):4679. doi: 10.1038/s41598-018-22724-9.

2017

Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny.
Crauste F, Mafille J, Boucinha L, Djebali S, Gandrillon O, Marvel J, Arpin C.
Cell Syst. 2017 Mar 22;4(3):306-317.e4. doi: 10.1016/j.cels.2017.01.014. Epub 2017 Feb 22.

Human Naive and Memory T Cells Display Opposite Migratory Responses to Sphingosine-1 Phosphate.
Drouillard A, Neyra A, Mathieu AL, Marçais A, Wencker M, Marvel J, Belot A, Walzer T.
J Immunol. 2018 Jan 15;200(2):551-557. doi: 10.4049/jimmunol.1701278. Epub 2017 Dec 13.

Two-Photon Photosensitizer-Polymer Conjugates for Combined Cancer Cell Death Induction and Two-Photon Fluorescence Imaging: Structure/Photodynamic Therapy Efficiency Relationship.
Cepraga C, Marotte S, Ben Daoud E, Favier A, Lanoë PH, Monnereau C, Baldeck P, Andraud C, Marvel J, Charreyre MT, Leverrier Y.
Biomacromolecules. 2017 Dec 11;18(12):4022-4033. doi: 10.1021/acs.biomac.7b01090.

2016

Immune signatures of protective spleen memory CD8 T cells.
Brinza L, Djebali S, Tomkowiak M, Mafille J, Loiseau C, Jouve PE, de Bernard S, Buffat L, Lina B, Ottmann M, Rosa-Calatrava M, Schicklin S, Bonnefoy N, Lauvau G, Grau M, Wencker M, Arpin C, Walzer T, Leverrier Y, Marvel J.
Sci Rep. 2016 Nov 24;6:37651. doi: 10.1038/srep37651.

Poly-functional and long-lasting anticancer immune response elicited by a safe attenuated Pseudomonas aeruginosa vector for antigens delivery.
Chauchet X, Hannani D, Djebali S, Laurin D, Polack B, Marvel J, Buffat L, Toussaint B, Le Gouëllec A.
Mol Ther Oncolytics. 2016 Dec 14;3:16033. doi: 10.1038/mto.2016.33.

IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling study.
Gao X, Arpin C, Marvel J, Prokopiou SA, Gandrillon O, Crauste F.
BMC Syst Biol. 2016 Aug 17;10(1):77. doi: 10.1186/s12918-016-0323-y.

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway.
Viel S, Marçais A, Guimaraes FS, Loftus R, Rabilloud J, Grau M, Degouve S, Djebali S, Sanlaville A, Charrier E, Bienvenu J, Marie JC, Caux C, Marvel J, Town L, Huntington ND, Bartholin L, Finlay D, Smyth MJ, Walzer T.
Sci Signal. 2016 Feb 16;9(415):ra19. doi: 10.1126/scisignal.aad1884.

2015

Human natural killer cells promote cross-presentation of tumor cell-derived antigens by dendritic cells.
Deauvieau F, Ollion V, Doffin AC, Achard C, Fonteneau JF, Verronese E, Durand I, Ghittoni R, Marvel J, Dezutter-Dambuyant C, Walzer T, Vie H, Perrot I, Goutagny N, Caux C, Valladeau-Guilemond J.
Int J Cancer. 2015 Mar 1;136(5):1085-94. doi: 10.1002/ijc.29087.

2014

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow.
Daussy C, Faure F, Mayol K, Viel S, Gasteiger G, Charrier E, Bienvenu J, Henry T, Debien E, Hasan UA, Marvel J, Yoh K, Takahashi S, Prinz I, de Bernard S, Buffat L, Walzer T.
J Exp Med. 2014 Mar 10;211(3):563-77. doi: 10.1084/jem.20131560.

Multiscale Modeling of the Early CD8 T-Cell Immune Response in Lymph Nodes: An Integrative Study.
Sotiris Prokopiou, Loic Barbarroux, Samuel Bernard, Julien Mafille, Yann Leverrier, Christophe Arpin, Jacqueline Marvel, Olivier Gandrillon, Fabien Crauste
Computation, MDPI, 2014, 2 (4), pp.159-181. 10.3390/computation2040159

2013

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.
Biroccio A, Cherfils-Vicini J, Augereau A, Pinte S, Bauwens S, Ye J, Simonet T, Horard B, Jamet K, Cervera L, Mendez-Bermudez A, Poncet D, Grataroli R, de Rodenbeeke CT, Salvati E, Rizzo A, Zizza P, Ricoul M, Cognet C, Kuilman T, Duret H, Lépinasse F, Marvel J, Verhoeyen E, Cosset FL, Peeper D, Smyth MJ, Londoño-Vallejo A, Sabatier L, Picco V, Pages G, Scoazec JY, Stoppacciaro A, Leonetti C, Vivier E, Gilson E.
Nat Cell Biol. 2013 Jul;15(7):818-28. doi: 10.1038/ncb2774.

Tumor Promotion by Intratumoral Plasmacytoid Dendritic Cells Is Reversed by TLR7 Ligand Treatment.
Le Mercier I, Poujol D, Sanlaville A, Sisirak V, Gobert M, Durand I, Dubois B, Treilleux I, Marvel J, Vlach J, Blay JY, Bendriss-Vermare N, Caux C, Puisieux I, Goutagny N.
Cancer Res. 2013 Aug 1; 73(15):818-28

S1PR5 is pivotal for the homeostasis of patrolling monocytes.
Debien E, Mayol K, Biajoux V, Daussy C, De Aguero MG, Taillardet M, Dagany N, Brinza L, Henry T, Dubois B, Kaiserlian D, Marvel J, Balabanian K, Walzer T.
Eur J Immunol. 2013 Jun;43(6):1667-75. doi: 10.1002/eji.201343312.

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.
Tomkowiak M, Ghittoni R, Teixeira M, Blanquier B, Szécsi J, Nègre D, Aubert D, Coupet CA, Brunner M, Verhoeyen E, Thoumas JL, Cosset FL, Leverrier Y, Marvel J.
Genesis. 2013 Mar;51(3):193-200. doi: 10.1002/dvg.22364.

2012

Synthesis of PEGylated gold nanostars and bipyramids for intracellular uptake.
Navarro JR, Manchon D, Lerouge F, Blanchard NP, Marotte S, Leverrier Y, Marvel J, Chaput F, Micouin G, Gabudean AM, Mosset A, Cottancin E, Baldeck PL, Kamada K, Parola S.
Nanotechnology. 2012 Nov 23;23(46):465602. doi: 10.1088/0957-4484/23/46/465602.

Negative regulation of NKG2D expression by IL-4 in memory CD8 T cells.
Ventre E, Brinza L, Schicklin S, Mafille J, Coupet CA, Marçais A, Djebali S, Jubin V, Walzer T, Marvel J.
J Immunol. 2012 Oct 1;189(7):3480-9.

NOD1 cooperates with TLR2 to enhance T cell receptor-mediated activation in CD8 T cells.
Mercier BC, Ventre E, Fogeron ML, Debaud AL, Tomkowiak M, Marvel J, Bonnefoy N.
PLoS One. 2012;7(7):e42170. doi: 10.1371/journal.pone.0042170.

Development of antigen cross-presentation capacity in dendritic cells.
Dresch C, Leverrier Y, Marvel J, Shortman K.
Trends Immunol. 2012 Aug;33(8):381-8. doi: 10.1016/j.it.2012.04.009.

T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production.
Jubin V, Ventre E, Leverrier Y, Djebali S, Mayol K, Tomkowiak M, Mafille J, Teixeira M, Teoh DY, Lina B, Walzer T, Arpin C, Marvel J.
Immunol Res. 2012 Jun;52(3):284-93. doi: 10.1007/s12026-012-8340-4.

Mathematical model of the primary CD8 T cell immune response: stability analysis of a nonlinear age-structured system.
Terry E, Marvel J, Arpin C, Gandrillon O, Crauste F.
J Math Biol. 2012 Aug;65(2):263-91. doi: 10.1007/s00285-011-0459-8.

2011

Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking.
Mayol K, Biajoux V, Marvel J, Balabanian K, Walzer T.
Blood. 2011 Nov 3;118(18):4863-71. doi: 10.1182/blood-2011-06-362574.

Photodynamic therapy and two-photon bio-imaging applications of hydrophobic chromophores through amphiphilic polymer delivery.
Gallavardin T, Maurin M, Marotte S, Simon T, Gabudean AM, Bretonnière Y, Lindgren M, Lerouge F, Baldeck PL, Stéphan O, Leverrier Y, Marvel J, Parola S, Maury O, Andraud C.
Photochem Photobiol Sci. 2011 Jul;10(7):1216-25. doi: 10.1039/c0pp00381f.

CpG promotes cross-presentation of dead cell-associated antigens by pre-CD8α+ dendritic cells [corrected].
de Brito C, Tomkowiak M, Ghittoni R, Caux C, Leverrier Y, Marvel J.
J Immunol. 2011 Feb 1;186(3):1503-11. doi: 10.4049/jimmunol.1001022.

2010

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells.
Crozat K, Guiton R, Contreras V, Feuillet V, Dutertre CA, Ventre E, Vu Manh TP, Baranek T, Storset AK, Marvel J, Boudinot P, Hosmalin A, Schwartz-Cornil I, Dalod M.
J Exp Med. 2010 Jun 7;207(6):1283-92. doi: 10.1084/jem.20100223.

CD137 in NK cells.
Marvel J, Walzer T.
Blood. 2010 Apr 15;115(15):2987-8. doi: 10.1182/blood-2010-01-261404.

EuroPhenome: a repository for high-throughput mouse phenotyping data.
Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J; EUMODIC Consortium, de Angelis MH, Brown SD, Hancock JM, Mallon AM.
Nucleic Acids Res. 2010 Jan;38(Database issue):D577-85. doi: 10.1093/nar/gkp1007.

2009

Overexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibition.
Deniaud E, Baguet J, Chalard R, Blanquier B, Brinza L, Meunier J, Michallet MC, Laugraud A, Ah-Soon C, Wierinckx A, Castellazzi M, Lachuer J, Gautier C, Marvel J, Leverrier Y.
PLoS One. 2009 Sep 15;4(9):e7035. doi: 10.1371/journal.pone.0007035.

TLR2 engagement on memory CD8(+) T cells improves their cytokine-mediated proliferation and IFN-gamma secretion in the absence of Ag.
Cottalorda A, Mercier BC, Mbitikon-Kobo FM, Arpin C, Teoh DY, McMichael A, Marvel J, Bonnefoy-Bérard N.
Eur J Immunol. 2009 Oct;39(10):2673-81. doi: 10.1002/eji.200939627.

Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions.
Mbitikon-Kobo FM, Vocanson M, Michallet MC, Tomkowiak M, Cottalorda A, Angelov GS, Coupet CA, Djebali S, Marçais A, Dubois B, Bonnefoy-Bérard N, Nicolas JF, Arpin C, Marvel J.
J Immunol. 2009 Mar 15;182(6):3846-54. doi: 10.4049/jimmunol.0802438.

TLR2 engagement on CD8 T cells enables generation of functional memory cells in response to a suboptimal TCR signal.
Mercier BC, Cottalorda A, Coupet CA, Marvel J, Bonnefoy-Bérard N.
J Immunol. 2009 Feb 15;182(4):1860-7. doi: 10.4049/jimmunol.0801167.

 

Patents
1. INSERM Licence agreement, anti-mouse CCL5 antibody (clone 2E9)
2. European Patent submitted (n° 1000175638, application n° EP12306646.6, 21 December 2012): Methods and Kits for detecting antigen-induced memory CD8+ T cells