Publications

Liste complète actualisée: Google Scholar

2026:

• IRF2 deficiency disrupts pyroptosis, NK cell interferon-g production and resistance to Francisella

Cornut M, Djebali S^#, Rondeau E^#, Dayet S, Fayolle T, Haagen J, Fallone L, Rousseaux N, Caspar E, Marcotte M, Martin A, Courteboeuf E, Deschamp-Biboulet M, Teixeira M, Marvel J, Py BF, Walzer T, Marcais A, Henry T^@, Bourdonnay E^@

EMBO rep., 2026 Jan 28

• SpeckSeq enables high-throughput functional stratification of MEFV variants in autoinflammatory diseases

Bronnec P, Dalmon S, Briand C, Allatif O, Broly M, Marcotte M, Lombardi G, Barthes K, Martel N, Hughes S, Gillet B, Mihlavet F, Atilgan A, Bachelez H, Palmeri S, Prigione I, Madrange M, Savey L, Moutschen M, Jeru I, El Moussaoui M, Belot A, Sbidian E, Carbone A, Jamilloux Y, Gattorno M, Smahi A, Georgin-Lavialle S, Boursier G, Magnotti F^@, Henry T^@

J. Exp. Med 2026 Feb 2

2025:

• PRESCOTT: a population aware, epistatic and structural model accurately predicts missense effect

Mustafa Tepkinar, Laurent David, Henry T, carbone A

Genome Biology, 2025 May 6; 26(1):113

2024:

• IFN-g licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes

Martin A, Caron S, Marcotte M, Bronnec P, Garneret E, Martel N, Maalouf G, Sève P, Saadoun D, Jamilloux Y^@, Henry T^@

iScience, 2024 Dec10; 28(1) 

2023:

• Pathogenicity and virulence of Francisella tularensis

Degabriel M, Valeva S, Boisset S, Henry T

Virulence, 2023 Dec; 14(1) (Signature review)

• Comparative study of GBP recruitment on two cytosol-dwelling pathogens, Francisella novicida and Shigella flexneri, highlights differences in GBP repertoire and in GBP1 requirements

Valeva S^#, Degabriel M^#, Michal F, Gay G, Rohde JR, Randow F, Lagrange B, Henry T

Pathog. Dis., 2023 Jan 17

• Mutations in the B30.2 and the central helical scaffold domains of pyrin differentially affect inflammasome activation

Chirita D, Bronnec P, Magnotti F, Dalmon S, Martin A, Popoff M, Gerfaud-Valentin M, Sève P, Belot A, Contis A, Duquesne A, Nocturne G, Lemelle I, Georgin-Lavialle S, Boursier G, Touitou I, Jamilloux Y, Henry T

Cell Death Dis. 14,213, 2023 

2022:

• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

Magnotti F, Chirita D, Dalmon S, Martin A, Bronnec P, Sousa J, Helynck O, Lee W, Kastner DL, Chae JJ, McDermott M, Belot A, Popoff M, Sève P, Georgin-Lavialle S, Munier-Lehmann H, Tran TA, De Langhe E, Wouters C, Jamilloux Y^@, Henry T^@(^@co-senior author)

Cell reports, 2022 Oct 11

2021:

• ALPK1 gene mutations drive autoinflammation with ectodermal dysplasia and progressive vision loss

Jamilloux Y, Mathis T, Grunewald O, Dollfuss H, Henry T, Sève P, Meunier I

Journal of Clinical Immunology, 2021 June 222020:

• A fast diagnostic test for familial Mediterranean fever based on a kinase inhibitor

Magnotti F, Malsot T, Georgin-Lavialle S, Abbas F, Martin A, Belot A, Fauter M, Rabilloud M, Gerfaud-Valentin M, Sève P, Duquesne A, Hot A, Durupt S, Savey L, Giurgea I, Grateau G, Henry T^@, and Jamilloux Y^@ (^@co-senior author)

Annals of the Rheumatic Diseases, 2020 Oct 9

2019:

• Pyrin dephosphorylation is sufficient to trigger inflammasome activation in Familial Mediterranean Fever patients.

Magnotti F, Lefeuvre L, Benezech S, Malsot T, Waeckel L, Martin A, Kerever S, Chirita D, Desjonqueres M, Duquesne A, Gerfaud-Valentin M, Laurent A, Sève P, Popoff MR, Walzer T, Belot A, Jamilloux Y^@, Henry T^@ (^@co-senior author)

EMBO Mol Med. 2019 Oct 7

• A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells.

Benaoudia S, Martin A, Puig Gamez M, Gay G, Lagrange B, Cornut M, Krasnykov K, Claude JB, Bourgeois CF, Hughes S, Gillet B, Allatif O, Corbin A, Ricci R, Henry T.

EMBO Rep. 2019 Jul 29

2018:

• Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin.

Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, Vandenesch F, Van Strijp JAG, Jan Lebbink R, Haas PA, Henry T^@, Spaan AN^@(^@co-senior author)

Nature Microbiol. 2018 May 7

• Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella highlighting functional differences with murine caspase-11

Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, Martin A, Di Lorenzo F, Py FB, Molinaro A, Henry T

Nature Communications, 2018 Jan; 9 (1), 242

• Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome

Jamilloux Y*, Lefeuvre L*, Magnotti F*, Martin A, Benezech S, Allatif O, Penel-Page M, Hentgen V, Sève P,  Gerfaud-Valentin M, Duquesne A, Desjonquères M, Laurent A, Rémy-Piccolo V, Cimaz R, Cantarini L, Bourdonnay E, Walzer T, Py BF, Belot A, Henry T.

Rheumatology, 2018 Jan 1;57(1):100-111.

2017:

• IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection

Wallet P*, Benaoudia S*, Mosnier A, Lagrange B, Martin A, Lindgren H, Golovlev I, Michal F, Basso P, Djebali S, Provost A, Allatif O, Meunier E, Broz P, Yamamoto M, Py BF, Faudry E, Sjöstedt A, Henry T.

Plos Pathogens, 2017 Oct2;13(10).

2016:

• Francisella tularensis IglG belongs to a novel family of PAAR-like T6SS proteins and harbors a unique N-terminal extension required for virulence

Rigard M, Bröms JE, Mosnier A, Hologne M, Martin A, Lindgren L, Punginelli C, Lays C, Walker O, Charbit A, Telouk P, Conlan W, Terradot L^@, Sjöstedt A^@, Henry T^@(^@co-senior author)

PLOS Pathogens, 2016, Aug 24