Séminaire CIRI : Dr. Alain Kohl
« Targeting immunity to arboviruses across vertebrate and mosquitos »
| When |
Feb 23, 2023
from 11:00 AM to 12:00 PM |
|---|---|
| Where | Salle des thèses, ENS-Lyon |
| Contact Name | François-Loïc Cosset. |
Dr. Alain KOHL ((MRC-University of Glasgow Centre for Virus Research): " Targeting immunity to arboviruses across vertebrate and mosquitos "
Abstract: Arboviruses replicate in both vertebrates and arthropods, which results in the induction of immune responses. Immunity can end up being a double edged sword and unbalances can result in disease, but it can also be targeted for interventions provided targets are known and amenable for intervention. I will discuss findings with tick-borne Dabie bandavirus to show how disease in vertebrates can be investigated and targeted; and also show potential opportunities for targets in mosquito immunity that may be suitable for manipulation and reduce the burden of arbovirus transmission.