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New methods to unveil host-microbe interaction mechanisms along the microbiota-gut-brain-axis
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Gut Microbes: Moradian H., Gabriel T., Barrau M., Roblin X., Paul S. DOI:10.1080/19490976.2024.2351520
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Paul S - GIMAP
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Actualités
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Immunogenicity and efficacy of heterologous ChAdOx1–BNT162b2 vaccination
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Pozzeto et al. Nature. December 2021
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Paul S - GIMAP
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A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity
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During liver carcinogenesis, the first enzyme of glycolysis GCK is replaced in hepatocytes by the hexokinase HK2. We show that it critically contributes to metabolic reprogramming and inhibition of innate immunity associated to liver cancer development.
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VIDALAIN PO - VIRIMI
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New article about staphylococcal pneumonia
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Prognostic factors of severe community-acquired staphylococcal pneumonia in France
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Vandenesch F - Stapath
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The Journal of Immunology : last publication LYACTS team
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Walzer T - LYACTS
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Inhibitory Effect of IL-1b on HBV and HDV Replication and HBs Antigen-Dependent Modulation of Its Secretion by Macrophages
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Delphin et al., Viruses, 2022 / Team HepVir
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Durantel D - HepVir
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Evidence for long-term association of virion-delivered Hepatitis B virus Core protein with cccDNA independently of viral protein production
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Lucifora, Pastor et al., JHep Reports, 2021 / Team HepVir
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Durantel D - HepVir
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New preprint on the pyrin inflammasome
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Check out our new preprint in BioRxiv by Flora and colleagues on the discovery of novel activators of the pyrin inflammasome.
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Henry T - I2BA
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Inducers of the NF-κB pathways impair Hepatitis Delta virus (HDV) replication & strongly decrease progeny infectivity in vitro
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Michelet, Alfaiate, Chardès et al., J Hep Reports, 2022 / Team HepVir
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Durantel D - HepVir
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ALPK1 gene mutations drive autoinflammation with ectodermal dysplasia and progressive vision loss
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ALPK1 is a kinase sensing a bacterial metabolite from the LPS biosynthesis pathway. Our favorite clinician describes a new family of patients. This rare monogenic disease associated with vision loss is still poorly known in the field of autoinflammation and this description of a new family of patients should raise awareness on the inflammatory symptoms associated with this disease.
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Henry T - I2BA
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