Centre International de Recherche en Infectiologie

Interferon-dependent and independent mechanisms drive Hepatitis Delta Virus interference on Hepatitis B Virus RNA production: Lucifora et al., Journal of Hepatology, 2023 / Team HepVir
Rattaché à Équipes / Durantel D - HepVir / Quoi de neuf pour nous ?
Interleukins 15 and 18 synergistically prime the antitumor function of natural killer cells through noncanonical activation of mTORC1: Natural killer (NK) cells have antitumor activity that is primed by IL-15 and IL-18, components of a cytokine cocktail used in NK cell–based cancer immunotherapy. Fallone et al. found that IL-15 and IL-18 synergized to activate the complex mTORC1, which resulted in increased proliferation and function of both mouse and human NK cells. IL-15 and IL-18 stimulated mTORC1 activity through distinct pathways not previously implicated in its regulation. The combination of IL-15 and IL-18 improved the survival of mice engrafted with tumor cells, suggesting a therapeutic strategy to enhance the efficacy of NK cell–based cancer immunotherapy
Rattaché à Équipes / Walzer T - LYACTS / Actualités
Inverted direct allorecognition triggers early donor-specific antibody responses after transplantation: X.Charmetant, CC.Chen, S.Hamada [...] and O.Thaunat Science Translational Medicine, 2022
Rattaché à Équipes / Thaunat O - NOPAB / Actualités
JEM, 2021, August 06 :Early nasal type I IFN immunity against SARS-CoV-2 is compromised in patients with autoantibodies against type I IFNs: Rattaché à Équipes / Walzer T - LYACTS / Actualités
LACC1-associated JIA linked to autophagy defects in macrophages: Rattaché à Équipes / Walzer T - LYACTS / Actualités
Lipoprotein receptors: A little grease for enveloped viruses to open the lock?: François-Loïc Cosset and Solène Denolly. JBC, 2024. DOI: 10.1016/j.jbc.2024.107849
Rattaché à Équipes / Cosset FL - EVIR / Actualités
Loss of hepatitis D virus infectivity upon farnesyl transferase inhibitor treatment associates with increasing RNA editing rates revealed by a new RT-ddPCR method: Verrier et al., Antiviral Research, 2022 / Team HepVir
Rattaché à Équipes / Durantel D - HepVir / Quoi de neuf pour nous ?
Lung virome convergence precedes hospital-acquired pneumonia in intubated critically ill patients: Lung virome convergence precedes hospital-acquired pneumonia in intubated critically ill patients Anani et al. Cell Rep Medicine - Team VirPath-CARVI
Rattaché à Équipes / … / B. Lina group / Equipe CARVI (O. Terrier/S. Trouillet-Assant)
Measles Virus-Imposed Remodeling of the Autophagy Machinery Determines the Outcome of Bacterial Coinfection: Claviere M, Lavedrine A, Lamiral G, Bonnet M, Verlhac P, Petkova DS, Espert L, Duclaux-Loras R, Lucifora J, Rivoire M, Boschetti G, Nancey S, Rozières A, Viret C, Faure M. Autophagy. 2022 Jul 28.
Rattaché à Équipes / Faure M - APY / Actualités
mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice: Moreews M ; Mathieu AL, Pouxvielh K... Marçais A, Walzer T, Belot A
Rattaché à Équipes / Walzer T - LYACTS / Actualités

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