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You are here: Home / About us / Events / Séminaire CIRI : Dr. Philippe AFONSO

Séminaire CIRI : Dr. Philippe AFONSO

"Neuroinvasion by HTLV and ZIKV: how blood-borne viruses cross the blood brain barrier"
When Mar 01, 2022
from 11:00 AM to 12:00 PM
Where Salle des thèses, ENS-Lyon
Contact Name

Philippe AFONSO (Unité d’Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur, Université de Paris, CNRS) : "Neuroinvasion by HTLV and ZIKV: how blood-borne viruses cross the blood brain barrier"

Abstract: The central nervous system (CNS) is naturally protected from blood-borne viruses by a series of selective interfaces, among which the blood-brain barrier (BBB). The BBB is the largest CNS/blood interface, composed primarily of a continuous endothelium sealed with tight junctions. Over the years, we have evidenced factors regulating the interaction between BBB endothelial cell and viruses (namely the retrovirus HTLV-1 and the flavivirus ZIKV), in order to understand the mechanisms of neuroinvasion.

Hôte: François-Loïc Cosset.

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