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Understanding infectious diseases to better control them

The Centre International de Recherche en Infectiologie (CIRI) is a joint research unit of the Lyon 1 University, Inserm, CNRS and the ENS de Lyon in partnership with VetAgro Sup, the Institut Pasteur and the Hospices Civils de Lyon. The CIRI gathers the scientific and medical research communities with complementary disciplinary backgrounds grouped in 3 specialties working together with the objective to understand host-microbe interactions to better fight infectious diseases.

Discover the CIRI: General presentation, Teams, Teaching, Clinical research, Organization, The 3 specialties and Transversal projects, Jobs and internship offers, Contact & Localization.





Aug 08, 2022 Measles Virus-Imposed Remodeling of the Autophagy Machinery Determines the Outcome of Bacterial Coinfection

Claviere M, Lavedrine A, Lamiral G, Bonnet M, Verlhac P, Petkova DS, Espert L, Duclaux-Loras R, Lucifora J, Rivoire M, Boschetti G, Nancey S, (...)

Jul 29, 2022 Insights on the antiviral mechanisms of action of the TLR1/2 agonist Pam3CSK4 in hepatitis B virus (HBV)-infected hepatocytes

Desmares et al., Antiviral Research, 2022 / Team HepVir

Jul 12, 2022 The broad viral inhibitors IFITMs can regulate Golgi trafficking

Li Zhong, Yuxin Song, Federico Marziali, Rustem Uzbekov, Xuan-Nhi Nguyen, Chloé Journo, Philippe Roingeard, Andrea Cimarelli


Sep 10, 2021 Selective Autophagy Receptors in Antiviral Defense.

Viret C, Duclaux-Loras R, Nancey S, Rozières A, Faure M.Trends Microbiol. 2021 Sep;29(9):798-810.

Apr 19, 2021 Regulatory Networks of the T4SS Control: From Host Cell Sensing to the Biogenesis and the Activity during the Infection

Jaboulay et al. J Mol Biol 2021 April 30

Mar 30, 2021 Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond

Pastor F et al., Frontiers in Microbology, 2021 / Team HepVir


Last seminars

Jul 12, 2022 CIRI seminar: Pr. Paul GUICHARD

"Expansion microscopy for Structural cell biology: from centriole architecture to human diseases"

Jul 04, 2022 Séminaire CIRI : Pr. Stephan URBAN

"Discovery and development of Hepcludex/bulevirtide, the first approved drug for chronic Hepatitis (...)

Jun 28, 2022 CIRI seminar: Dr Thomas S KUPPER

"The formation and role of resident memory T cells in skin inflammatory diseases"

Jun 21, 2022 CIRI seminar cancelled : Pr. Soren Riis PALUDAN

"Activation of signaling by the cGAS-STING pathway in innate immunity"

Jun 14, 2022 Séminaire CIRI : Dr. Sandrine BOURDOULOUS

"New strategies to combat pathogenic bacteria: the example of Neisseria meningitidis"


Sep 18, 2022 Congrès International HBV 2022

Biologie des virus des hépatites B et D

Last events

Jan 26, 2022 Kick-off meeting Equipex InfectioTron
May 10, 2021 Interview de Olivier Hequet

Etude COVIDEP : un essai clinique pour limiter la phase "d'hyper inflammation" liée au Covid-19

Thesis defenses

Oct 05, 2021 PhD defense of Marion Delphin, team HepVir

Polarization of Hepatic Macrophages by HBsAg, a means to an end for viral maintenance