-
Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells effector functions
-
S.Wang, M.Prieux, S.de Bernard, M.Dubois, D.Laubreton , S.Djebali, M.Zala, C.Arpin, L.Genestier, Y.Leverrier, O.Gandrillon, F.Crauste, W.Jiang, J.Marvel
Rattaché à
Équipes
/
Marvel J - ICL
/
Actualités
-
Mucosal Vaccination with Live Attenuated Bordetella bronchiseptica Protects against Challenge in Wistar Rats
-
Vaccines: Miguelena Chamorro B., De Luca K., Swaminathan G., Rochereau N., Majorel J., Poulet H. Chanut B., Piney L., Mundt E., Paul S. https://www.mdpi.com/2076-393X/11/5/982
Rattaché à
Équipes
/
Paul S - GIMAP
/
Actualités
-
Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations
-
Clinical Microbiology Reviews: Miguelena Chamorro B., De Luca K., Swaminathan G., Longet S., Mundt E., Paul S. https://journals.asm.org/doi/10.1128/cmr.00164-22
Rattaché à
Équipes
/
Paul S - GIMAP
/
Actualités
-
Unique molecular signatures typify skin inflammation induced by chemical allergens and irritants
-
Lefevre MA , Nosbaum A, Rozieres A, Lenief V, Mosnier A, Cortial A, Prieux M, De Bernard S, Nourikyan J, Jouve PE, Buffat L, Hacard F, Ferrier-Lebouedec MC, Pralong P, Dzviga C, Herman A, Baeck M, Nicolas JF, Vocanson M. . Jaci. 2022. 6749(22)00884-3
Rattaché à
Équipes
/
Vocanson M - EIA
/
Actualités
-
Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus
-
Marie Jeanpierre, Jade Cognard, Maud Tusseau, ... Thierry Walzer, Frédéric Rieux-Laucat, Alexandre Belot, and Anne-Laure Mathieu ; J Exp Med 2024 Sep 2;221(9):e20232337. doi: 10.1084/jem.20232337.
Rattaché à
Équipes
/
Walzer T - LYACTS
/
Actualités
-
Tumor-induced natural killer cell dysfunction is a rapid and reversible process uncoupled from the expression of immune checkpoints
-
Kévin Pouxvielh, Marie Marotel, Annabelle Drouillard, Marine Villard, ... Olivier Thaunat, Antoine Marçais, Thierry Walzer /
Science Advances , 2024, Aug 28
Rattaché à
Équipes
/
Walzer T - LYACTS
/
Actualités
-
Insights on the antiviral mechanisms of action of the TLR1/2 agonist Pam3CSK4 in hepatitis B virus (HBV)-infected hepatocytes
-
Desmares et al., Antiviral Research, 2022 / Team HepVir
Rattaché à
Équipes
/
Durantel D - HepVir
/
Quoi de neuf pour nous ?
-
Enveloppement et sécrétion du CCHFV
-
The PACS-2 protein and trafficking motifs in CCHFV Gn and Gc cytoplasmic domains govern CCHFV assembly.
Gautam A, Lalande A, Ritter M, Freitas N, Lerolle S, Canus L, Amirache F, Lotteau V, Legros V, Cosset FL, Mathieu C and Boson B.
Emerg Microbes Infect. 2024. doi:10.1080/22221751.2024.2348508
Rattaché à
Équipes
/
Cosset FL - EVIR
/
Actualités
-
The broad viral inhibitors IFITMs can regulate Golgi trafficking
-
Li Zhong, Yuxin Song, Federico Marziali, Rustem Uzbekov, Xuan-Nhi Nguyen, Chloé Journo, Philippe Roingeard, Andrea Cimarelli
Rattaché à
Équipes
/
Cimarelli A - LP2L
/
Actualités
-
Interleukins 15 and 18 synergistically prime the antitumor function of natural killer cells through noncanonical activation of mTORC1
-
Natural killer (NK) cells have antitumor activity that is primed by IL-15 and IL-18, components of a cytokine cocktail used in NK cell–based cancer immunotherapy. Fallone et al. found that IL-15 and IL-18 synergized to activate the complex mTORC1, which resulted in increased proliferation and function of both mouse and human NK cells. IL-15 and IL-18 stimulated mTORC1 activity through distinct pathways not previously implicated in its regulation. The combination of IL-15 and IL-18 improved the survival of mice engrafted with tumor cells, suggesting a therapeutic strategy to enhance the efficacy of NK cell–based cancer immunotherapy
Rattaché à
Équipes
/
Walzer T - LYACTS
/
Actualités
