CIRI — Centre International de Recherche en Infectiologie

Understanding infectious diseases to better control them

The CIRI (Centre International de Recherche en Infectiologie) brings together the scientific and medical research communities in infectious diseases and immunity in the Lyon-St Etienne area, with the University of Lyon 1, Inserm, CNRS and ENS de Lyon as main managing bodies, and Hospices Civils de Lyon and Université Jean Monnet as secondary managing bodies, and important partnerships with VetAgroSup and Institut Pasteur. More than 400 researchers with complementary disciplinary backgrounds are grouped into 3 main departments: immunologists, bacteriologists and virologists, some of them being as well as cancerologists and epidemiologists. They work together with the main objective of understanding the biology of microbes and the immune system, and the interactions between microbes and their hosts, in order to better combat infectious diseases and other illnesses involving the immune system.

Three departments working together: Bacteriology

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Publications: Lung virome convergence precedes hospital-acquired pneumonia in intubated critically ill patients
Lung virome convergence precedes hospital-acquired pneumonia in intubated critically ill patients Anani et al. Cell Rep Medicine - Team VirPath-CARVI; The dual-specificity kinase DYRK1A interacts with the Hepatitis B virus genome and regulates the production of viral RNA
Pastor et al., Plos One, 2024 / Team HepVir; Deciphering the phospho-signature induced by hepatitis B virus in primary human hepatocytes
Pastor et al., Frontiers Mircrobiology, 2024 / Team HepVir; Pivotal role of exogenous pyruvate in human natural killer cell metabolism
Nicolas Kern Coquillat, Louis Picq, Ameline Hamond, Pierre Megy, Sarah Benezech, Annabelle Drouillard, Nina Lager-Lachaud, Edern Cahoreau, Marielle Moreau, Lucie Fallone, Anne-Laure Mathieu, Floriant Bellvert, Carine Nizard, Anne-Laure Bulteau, Thierry Walzer, Antoine Marçais /// Nature Metabolism, 2025 Jan 3; Mucosal nirsevimab levels in respiratory syncytial virus breakthrough bronchiolitis
Pillet S, Cantais A, Noailly B, Jospin F, Zekre F, Boussetta-Charfi O, Chenafi-Adham S, Bourlet T, Fourati S, Paul S. Lancet Infect Dis. 2024. doi:10.1016/S1473-3099(24)00600-5.; Impaired mucosal IgA response in patients with severe COVID-19
Yaugel-Novoa M, Noailly B, Jospin F, Pizzorno A, Traversier A, Pozzetto B, Waeckel L, Longet S, Pillet S, Botelho-Nevers E, Rosa-Calatrava M, Bourlet T, Paul S. Emerg Microbes Infect. 2024. doi:10.1080/22221751.2024.2401940

News: Lookback on the IRCI Symposium 2025 (Immune Responses in Cancer and Infection); François Rousset lauréat des bourses "Starting" de l'ERC
Le Conseil européen de la recherche (ERC) a annoncé les lauréats 2025 de la bourse "Starting Grant". François Rousset (GenoMics) a obtenu avec succès cette bourse dédiée aux jeunes chercheurs et chercheuse portant des projets d'excellence, avec son projet "Conservation of defense and anti-defense mechanisms across the tree of life" (CODA).; Second edition of the CIRI's paella had a great success
Last friday on june 13th was organized CIRI's yearly paella for the second time. A festive afternoon which brought the CIRI together!; Stéphane Paul (GIMAP) parmi les nouveaux lauréats de l'Institut Universitaire de France (IUF)
L'Institut Universitaire de France a récemment nommé ses nouveaux membres pour cinq ans, parmi eux, Stephane Paul chef de l'équipe GIMAP et PU-PH; Exposition photo croisée entre le CIRI et un restaurant
Le 14 juin, retrouvez des photos du CIRI dans une exposition surprenante mélangeant gastronomie et sciences; 16 juin: matinée d'échange sur les relations chercheurs et journalistes à l'amphi anne l'huillier
Organisée par le service communication de l'ENS de Lyon.; Thomas Henry's work in comic strip format

Job offers: Postdoctoral position II - Intracellular Persister Biology
PERSIST Lab - Nicolas Personnic; Two years post-doc position on viral phylodynamics
Post-doc offer at the CERP (Center of Excellence in Respiratory Pathogens); Postdoctoral position I: Intracellular Persister Biology
PERSIST Lab - Nicolas Personnic; Open research positions
To heighten its projects on the molecular and cellular virology of the Crimean-Congo hemorrhagic fever virus (CCHFV), HEAL, the Hepatotropic & Emerging Agents Laboratory is seeking to recruit: - A (...); PhD position in skin immunity (EIA team)
A PhD under a "CIFRE convention" is opened in EIA team. It will start in September 2024.; Post-doc - Immuno-Therapy (updated)
EVIR Team: "Genetic reprogramming of B cells to enhance their therapeutic properties before autologous transfer"; Post-doctoral position in skin immunity
A 2-year post-doctoral position for a highly motivated and talented postdoctoral fellow is available in the team of Dr Marc Vocanson at the Centre International de Recherche en Infectiologie (CIRI), (...)