Publications
NLRP3 and inflammasomes
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Nadjar J, Monnier S, Bastien E, Huber AL, Oddou C, Bardoulet L, Leloup HB, Ichim G, Vanbelle C, Py BF, Destaing O, Petrilli V.
Sci Signal. 2024 Apr 23;17(833):eabn8003. doi: 10.1126/scisignal.abn8003.
Nat Immunol. 2025 Mar;26(3):337-339. doi: 10.1038/s41590-025-02093-y.
- Cosson C, Riou R, Py BF.
Med Sci (Paris). 2024 Oct;40(10):707-710. doi: 10.1051/medsci/2024110. French
Cescato M, Zhu YYJ, Le Corre L, Py BF, Georgin-Lavialle S, Rodero MP.
Cells. 2024 Aug 16;13(16):1365. doi: 10.3390/cells13161365. Review.
- Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation
C. Cosson, R. Riou, D. Patoli, T. Niu, A. Rey, M. Groslambert, C. De Rosny, E. Chatre, O. Allatif, T. Henry, F. Venet, F. Milhavet, G. Boursier, A. Belot, Y. Jamilloux, E. Merlin, A. Duquesne, G. Grateau, L. Savey, A. T. J. Maria, A. Pagnier, S. Poutrel, O. Lambotte, C. Mallebranche, S. Ardois, O. Richer, I. Lemelle, F. Rieux-Laucat, B. Bader-Meunier, Z. Amoura, I. Melki, L. Cuisset, I. Touitou, M. Geyer, S. Georgin-Lavialle, and B. F. Py
J. Exp. Med. 2024 May 6;221(5):e20231200; doi: 10.1084/jem.20231200.
Video summary by Benedicte Py:
Rémy Coudereau, Morgane Gossez, Bénédicte F Py, Thomas Henry, Anne-Claire Lukaszewicz, Guillaume Monneret and Fabienne Venet
Cells 2022, 11(20), 3306; doi:10.3390/cells11203306
Marlène Chemarin, Océane Dufies, Anastassia Mazet , Eva Mellan, Rémy Coudereau, Bénédicte F Py, Laurent Boyer, Fabienne Venet
Med Sci (Paris). 2022 Jun-Jul;38(6-7):545-552. doi: 10.1051/medsci/2022080. Review. [French].
Tingting Niu, Charlotte De Rosny, Séverine Chautard, Amaury Rey, Danish Patoli,
Marine Groslambert, Camille Cosson, Brice Lagrange, Zhirong Zhang, Orane Visvikis, Sabine Hacot, Maggy Hologne, Olivier Walker, Jeimin Wong, Ping Wang, Roméo Ricci, Thomas Henry, Laurent Boyer, Virginie Petrilli & Bénédicte F. Py
Nat Commun. 2021 Oct 6;12(1):5862. doi: 10.1038/s41467-021-26142-w
Groslambert M, Py BF.
J Inflamm Res. 2018 Sep 25;11:359-374. doi: 10.2147/JIR.S141220. Review.
Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, Martin A, Di Lorenzo F, Py BF, Molinaro A, Henry T.
Nat Commun. 2018 Jan 16;9(1):242. doi: 10.1038/s41467-017-02682-y
Groslambert M, Py BF.
Med Sci (Paris). 2018 Jan;34(1):47-53. doi: 10.1051/medsci/20183401013. Review. [French]
Teixeira M, Py BF, Bosc C, Laubreton D, Moutin MJ, Marvel J, Flamant F, Markossian S.
Sci Rep. 2018 Jan 11;8(1):474. doi: 10.1038/s41598-017-18826-5
Wallet P, Benouadia S, Mosnier A, Lagrange B, Martin A, Lindgren H, Golovlev I, Michal F, Basso P, Djebali S, Provost A, Allatif O, Meunier E, Broz P, Yamamoto M, Py BF, Faudry E, Sjostedt A, Henry T.
Plos Pathogens. 2017 Oct 2. doi: 10.1371/journal.ppat.1006630
Jamilloux Y, Lefeuvre L, Magnotti F, Martin A, Benezech S, Allatif O, Penel-Page M, Hentgen V, Sève P, Gerfaud-Valentin M, Duquesne A, Desjonquères M, Laurent A, Rémy-Piccolo V, Cimaz R, Cantarini L, Bourdonnay E, Walzer T, Py BF, Belot A, Henry T.
Rheumatology. 2017 Oct 12. doi: 10.1093/rheumatology/kex373
Yuan J, Najafov A, Py BF.
Cell. 2016 Dec 15;167(7):1693-1704. doi: 10.1016/j.cell.2016.11.047. Review.
- [Interleukin-1, inflammasome and autoinflammatory diseases.]
Jamilloux Y, Bourdonnay E, Gerfaud-Valentin M, Py BF, Lefeuvre L, Barba T, Broussolle C, Henry T, Seve P.
Rev Med Interne. 2016. S0248-8663(16):30472-6. doi: 10.1016/j.revmed.2016.07.007. Review. [French]
- Design, synthesis, and evaluation of acrylamide derivatives as direct NLRP3 inflammasome inhibitors.
Cocco M, Miglio G, Giorgis M, Garella D, Marini E, Costale A, Regazzoni L, Vistoli G, Orioli M, Massulaha-Ahmed R, Detraz-Durieux I, Groslambert M, Py BF, Bertinaria M.
Chem Med Chem. 2016. 11(16):1790-803. doi: 10.1002/cmdc.201600055
Py BF, Jin M, Desai BN, Penumaka A, Zhu H, Kober M, Dietrich A, Lipinski MM, Henry T, Clapham DE, Yuan J.
Cell Reports. 2014. 97(2):292-6. doi: 10.1016/j.celrep.2014.02.015
Juruj C, Lelogeais V, Pierini R, Perret M, Py BF, Jamilloux Y, Broz P, Faure M, Henry T.
Front Cell Infect Microbiol. 2013. 3-14. doi: 10.3389/fcimb.2013.00014
Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J.
Mol. Cell. 2013. 49(2):331-8. doi: 10.1016/j.molcel.2012.11.009
Réponse immunitaire au sepsis
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PD-L1+ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models.
Gossez M, Vigneron C, Vandermoeten A, Lepage M, Courcol L, Coudereau R, Paidassai H, Jallades L, Lopez J, Kandara K, Ortillon M, Mommert M, Fabri A, Peronnet E, Grosjean C, Buisson M, Lukaszewicz AC, Rimmelé T, Argaud L, Cour M; REALISM study group; RICO study group; Py BF, Thaunat O, Defrance T, Monneret G, Venet F.
Nat Commun. 2025 Mar 28;16(1):3030. doi: 10.1038/s41467-025-57706-9. Open Access
- Monneret G, Haem Rahimi M, Lukaszewicz AC, Venet F, Gossez M.
Expert Opin Pharmacother. 2024 Nov;25(16):2125-2133. doi: 10.1080/14656566.2024.2418987. Review
- T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19.
Venet F, Gossez M, Bidar F, Bodinier M, Coudereau R, Lukaszewicz AC, Tardiveau C, Brengel-Pesce K, Cheynet V, Cazalis MA, Pescarmona R, Garnier L, Ortillon M, Buisson M, Bouscambert-Duchamp M, Morfin-Sherpa F, Casalegno JS, Conti F, Rimmelé T, Argaud L, Cour M, Saadatian-Elahi M, Henaff L, Vanhems P, Monneret G.
eBioMedicine. 2022 Apr;78:103967. doi: 10.1016/j.ebiom.2022.103967
- Immune response to three doses of mRNA SARS-CoV-2 vaccines in CD19-targeted chimeric antigen receptor T cell immunotherapy recipients.
Sesques P, Bachy E, Ferrant E, Safar V, Gossez M, Morfin-Sherpa F, Venet F, Ader F.
Cancer Cell. 2022 Jan 25:S1535-6108(22)00012-5. doi: 10.1016/j.ccell.2022.01.010
- Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome.
Venet F, Cour M, Rimmelé T, Viel S, Yonis H, Coudereau R, Amaz C, Abraham P, Monard C, Casalegno JS, Brengel-Pesce K, Lukaszewicz AC, Argaud L, Monneret G; RICO study group.
Crit Care. 2021 Apr 12;25(1):140. doi: 10.1186/s13054-021-03558-w
- COVID-19: What type of cytokine storm are we dealing with?
Monneret G, Benlyamani I, Gossez M, Bermejo-Martin JF, Martín-Fernandez M, Sesques P, Wallet F, Venet F.
J Med Virol. 2021 Jan;93(1):197-198. doi: 10.1002/jmv.26317
Cochlin
Py BF, Gonzalez SF, Long K, Kim MS, Kim YA, Zhu H, Yao J, Degauque N, Villet R, Ymele-leki P, Gadjeva M, Pier GB, Carroll MC, Yuan J
Immunity. 2013. 38(5):1063-72. doi: 10.1016/j.immuni.2013.01.015
Yao J, Py BF, Zhu H, Bao J, Yuan J.
Journal of Biological Chemistry. 2010. 285(20):14909-19. doi: 10.1074/jbc.M110.106724
Other topics
Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J.
Proc Natl Acad Sci USA. 2010. 107(32):14164-9. doi: 10.1073/pnas.1009485107
Lipinski MM, Hoffman G, Ng A, Zhou W, Py BF, Hsu E, Liu X, Eisenberg J, Liu J, Blenis J, Xavier RJ, Yuan J.
Developmental Cell. 2010. 18(6):1041-1052. doi: 10.1016/j.devcel.2010.05.005
Py B, Basmaciogullari S, Bouchet J, Zarka M, Moura IC, Benhamou M, Monteiro RC, Hocini H, Madrid R, Benichou S.
PLoS ONE. 2009. 4(3). doi: 10.1371/journal.pone.0005006
Py BF, Boyce M, Yuan J.
Autophagy. 2009. 5(3):393-6. doi: 10.4161/auto.5.3.7762
Twig G, Elorza A, Molina A, Mohamed H, Wikstrom JD, Stiles L, Walzer G, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.
EMBO Journal. 2008. 27(2):433-46. doi: 10.1038/sj.emboj.7601963
Boyce M, Py BF, Ryazanov AG, Minden JS, Long K, Ma D, Yuan J.
Cell Death and Differentiation. 2008. doi: 10.1038/sj.cdd.4402296
- The Siva protein is a novel intracellular ligand of the CD4 receptor that promotes HIV-1 envelope-induced apoptosis in T-lymphoid cells.
Py B, Bouchet J, Jacquot G, Sol-Foulon N, Basmaciogullari S, Schwartz O, Biard-Piechaczyk M, Benichou S.
Apoptosis. 2007. 12(10):1879-92. doi: 10.1007/s10495-007-0106-4
Py BF, Lipinski MM, Yuan J.
Autophagy. 2007. 3(2):117-25. doi: 10.4161/auto.3618
Py B, Slomianny C, Auberger P, Petit PX, Benichou S.
Journal of Immunology. 2004. 172(7):4008-4017. doi: 10.4049/jimmunol.172.7.4008
Book chapters
Boyce M, Lipinski MM, Py BF, Yuan J.
in « Apoptosis: Physiology and Pathology of Cell Death » edited by Reed JC and Green DR, New York: Cambridge University Press; August 2011.