Team members

Adrien Bosseboeuf | Post-doc

During my past research experiences, I have studied diverse and complementary fields. Firstly, I did my PhD training at the Université de Normandie studying the self-renewal and the differentiation of spermatogonial stem cells and the antineoplastic action of peptides extracted from the stem cell niche. Then, I did a post-doc at Université de Nantes - CRCINA (Centre de Recherche en Cancérologie et Immunologie de Nantes-Angers) deciphering the link between chronic infections and the haematological malignancy Multiple Myeloma. Next, I enrolled another post-doc at the department of pathology of the medical school of Albuquerque (USA) developing a human cellular model of multiple myeloma using a patient-derived pathogen-specific BCR.

I have joined the VIV Team in January 2021 and my interests focuse on (i) the dynamics of the molecular events orchestrating the activation of cells against viral infection and (ii) the development of a pDC cell model suitable for genetic editing.

Alicia Bellomo | Post-doc

I did my PhD training at the Centre d’immunologie Marseille Luminy (CIML), focusing on red pulp fibroblasts and their role as cellular niche for red pulp macrophages in the mouse spleen. I have joined the lab for my Post-doc in October 2020.

I’m interested in the activation profile of pDCs in the context of SARS CoV2 infection and the molecular mechanisms regulating the interaction of pDCs with B cells in autoimmune diseases.

Célia Nuovo | PhD student

I am a graduate of the Master ‘Infectiologie Fondamentale’ at Université Lyon 1'. I first joined the lab for my M2 internship in January 2021 and I now pursue for a PhD. Current COVID19 pandemic enlightens the need to improve our knowledge on the interaction of respiratory viruses with its host cells. I am studying this question, focusing on the interferon response triggered upon infection.

Elodie Décembre | Engineer (AI)

I have been an engineer with Marlene at CIRI since 2011. In 2016, I obtained an INSERM tenured position. I am studying the behaviour of pDCs in the context of various viral infections. Especially, I am developing novel cell models for pDC study. I have set up the methods for the study in our lab of viruses of distinct family, including more recently SARS-CoV-2.

Garima Joshi | PhD student

I am from India and did my BSc in Microbiology and MSc in Biomedical Science at the University of Delhi in India. Awarded by a scholarship from the French government, I then did my M1 & M2 Master in Chemistry and Life Sciences at the PSL University, Paris. I joined the lab in February 2020 for my Master internship, and now pursue in the Team for my PhD training. I am a student representative of BMIC doctoral school since January, 2021.

I am interested in studying innate immune response against viruses, especially elucidating the carrier of the immuno-stimulatory RNA from virally infected cells to the pDCs, and the possible negative signals.

Manon Venet | IE

I have been an engineer at CIRI since 2018. I am developing methods to define response of immune cells at the single cell level - with spatial resolution - in infected tissues by using multiplexed RNA FISH technology and immunostaining now analyse with multicolor confocal microscope analysis. I am interested by different viral infections including dengue and Chikugunya viruses and more recently, I also study the modulation of the innate response in SARS-Cov2 infected patients.

Margarida Sa Ribeiro | PhD student

After holding a MSc in Biomedical Research from the University of Coimbra in Portugal, I earned a an ERAMUS-fellowship to do an internship in immunology at the Institut Pasteur Paris. In July 2019 I started my PhD training in the VIV team, I am developing a new methodology for studying the dynamics of antiviral response at single-cell resolution. My research interest are primarily to understand how virus interacts and regulates the host cell.

Marlène Dreux | Team Leader

I have been leading the CIRI team since 2015. I really enjoy working with my great colleagues on virus/host interactions. Our research program encompasses aspects of virology, immunology and cell biology, ranging from the in vitro study of the molecular basis of the innate immune response and viral counteractions, to in vivo study and cross-talks between different antiviral pathways.