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Deciphering Legionella effector delivery by Icm/Dot secretion system reveals a new role for c-diGMP signaling

Unreported control of Type 4 secretion by the second messenger c-di-GMP signaling is revealed

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New article about staphylococcal pneumonia

Prognostic factors of severe community-acquired staphylococcal pneumonia in France

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Mar 31, 2021 A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity

During liver carcinogenesis, the first enzyme of glycolysis GCK is replaced in hepatocytes by the hexokinase HK2. We show that it critically contributes to metabolic reprogramming and inhibition of innate immunity associated to liver cancer development.

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